when I press the remote nothing happens,changed batteries still nothing,so I tried programming a new and the car doesn't repond.
Does anyone have any ideas what it may be.Thanks.

1. Are the remotes working ?
2. Is the battery flat or put in wrong ?
3. The remotes break easily when inserting new batteries and there is a chance that the holder the battery is sitting in is loose and is not making contact with the circuit board of the remote and might have to be resoldered.

If all else fails take it to a Ford dealership and get them to program it for you.